%20%D0%B1%D0%B5%D0%B7%20%D0%BE%D1%87%D0%B8%D1%81%D1%82%D0%BA%D0%B8%20%E2%80%94%20%D0%BA%D0%BE%D0%BF%D0%B8%D1%8F.jpg "Chemists Simplify Synthesis of Drugs Involving Amide Groups")
Chemists Simplify Synthesis of Drugs Involving Amide Groups
Chemists from HSE University and the Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences (INEOS RAS) have developed a new method for synthesising amides, essential compounds in drug production. Using a ruthenium catalyst and carbon monoxide under precisely controlled reaction conditions, they successfully obtained the target product without by-products or complex purification steps. The method has already been tested for synthesising a key component of Vorinostat, a drug used to treat T-cell lymphoma. This approach could lower the cost of the drug by orders of magnitude. The paper has been published in the Journal of Catalysis. The study was supported by the Russian Science Foundation.
3 April
Deadline for applications to present academic reports - January 20, 2025